• Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis 

      Cassini, Alessandro; Högberg, Liselotte Diaz; Plachouras, Diamantis; Quattrocchi, Annalisa; Hoxha, Ana; Simonsen, Gunnar Skov; Colomb-Cotinat, Mélanie; Kretzschmar, Mirjam E.; Devleesschauwer, Brecht; Cecchini, Michele; Ouakrim, Driss Ait; Oliveira, Tiago Cravo; Struelens, Marc J.; Suetens, Carl; Monnet, Dominique L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-05)
      <i>Background</i> - Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed to estimate the burden of infections caused by antibiotic-resistant bacteria of public health concern in countries of the EU and European Economic Area (EEA) in 2015, measured in number of ...
    • Cross-border spread of blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae: a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019 

      Ludden, Catherine; Lötsch, Felix; Alm, Erik; Kumar, Narender; Johansson, Karin; Albiger, Barbara; Huang, Te-Din; Denis, Olivier; Hammerum, Anette M.; Hasman, Henrik; Jalava, Jari; Räisänen, Kati; Dortet, Laurent; Jousset, Agnès B.; Gatermann, Sören; Haller, Sebastian; Cormican, Martin; Brennan, Wendy; Grosso, Maria Del; Monaco, Monica; Schouls, Leo; Samuelsen, Ørjan; Pirš, Mateja; Cerar, Tjaša; Oteo-Iglesias, Jésus; Pérez-Vázquez, Maria; Sjöström, Karin; Edquist, Petra; Hopkins, Katie L.; Struelens, Marc J.; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-21)
      An alert regarding an outbreak of carbapenem-resistant <i>Klebsiella pneumoniae</i> carrying <i>bla</i> <sub>NDM-1</sub> and <i>bla</i> <sub>OXA-48</sub> carbapenemase-encoding genes was sent by Germany to European Union (EU)/European Economic Area (EEA) countries in October 2019. Since only limited whole genome sequencing (WGS) data on <i>bla</i> <sub>NDM-1-</sub> and <i>bla</i> <sub>OXA-48</sub>-positive ...
    • Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022 

      Linkevicius, Marius; Bonnin, Rémy A; Alm, Erik; Svartström, Olov; Apfalter, Petra; Hartl, Rainer; Hasman, Henrik; Roer, Louise; Räisänen, Kati; Dortet, Laurent; Pfennigwerth, Niels; Hans, Jörg B; Tóth, Ákos; Buzgó, Lilla; Cormican, Martin; Delappe, Niall; Monaco, Monica; Giufrè, Maria; Hendrickx, Antoni Pa; Samuelsen, Ørjan; Pöntinen, Anna Kaarina; Caniça, Manuela; Manageiro, Vera; Oteo-Iglesias, Jesús; Pérez-Vázquez, María; Westmo, Karin; Mäkitalo, Barbro; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-11)
      Whole genome sequencing data of 874 Escherichia coli isolates carrying blaNDM-5 from 13 European Union/ European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were ...
    • Staphylococcus aureus bloodstream infections: Diverging trends of meticillin-resistant and meticillin-susceptible isolates, EU/EEA, 2005 to 2018 

      Gagliotti, Carlo; Högberg, Liselotte Diaz; Billström, Hanna; Eckmanns, Tim; Giske, Christian G.; Heuer, Ole E.; Jarlier, Vincent; Kahlmeter, Gunnar; Wong, Danilo Lo Fo; Monen, Jos; Murchan, Stephen; Simonsen, Gunnar Skov; Šubelj, Maja; Andrašević, Arjana Tambić; Żabicka, Dorota; Žemličková, Helena; Monnet, Dominique L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-18)
      Background: Invasive infections caused by Staphylococcus aureus have high clinical and epidemiological relevance. It is therefore important to monitor the S. aureus trends using suitable methods. Aim: The study aimed to describe the trends of bloodstream infections (BSI) caused by meticillin-resistant S. aureus (MRSA) and meticillin-susceptible S. aureus (MSSA) in the European Union (EU) and the ...
    • Strong correlation between the rates of intrinsically antibiotic-resistant species and the rates of acquired resistance in Gram-negative species causing bacteraemia, EU/EEA, 2016 

      Jarlier, Vincent; Högberg, Liselotte Diaz; Heuer, Ole E.; Campos, Josó; Eckmanns, Tim; Giske, Christian G.; Grundmann, Hajo; Johnson, Alan P.; Kahlmeter, Gunnar; Monen, Jos; Pantosti, Annalisa; Rossolini, Gian Maria; van de Sande-Bruinsma, Nienke; Vatopoulos, Alkiviadis; Żabicka, Dorota; Žemličková, Helena; Monnet, Dominique L.; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-15)
      <i>Background</i> - Antibiotic resistance, either intrinsic or acquired, is a major obstacle for treating bacterial infections.<p><p> <i>Aim</i> - Our objective was to compare the country-specific species distribution of the four Gram-negative species <i>Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa</i> and <i>Acinetobacter</i> species and the proportions of selected acquired ...